A Research Study On Platelet Rich Plasma - 3304 Words

Abstract Background: Platelet-rich plasma (PRP) is defined as a high concentration of platelets suspended in a small volume of plasma and was proposed for periodontal tissue regeneration. However, although it has been widely studied, there is much controversy on its efficacy. Purpose: To study and meta-analyze the effectiveness by means of clinical attachment level, probing depth reduction, bleeding, suppuration and recession of PRP for periodontal intrabony defects on randomized clinical trials (RCT) Material and methods: An electronic literature search was conducted by two reviewers (AR and AM) in several databases up to February 2014. The PICO question was: Do intrabony defects in treatment for periodontal regeneration with PRP have a higher or similar efficacy that other periodontal regeneration treatments? Articles were included in this systematic review if they were RCT with10 or more human subjects, reporting the radiographic and clinical outcomes PRP for guided tissue regeneration in intrabony periodontal defects. Random effects meta-analyses of the selected studies were applied to avoid any bias being caused by methodological differences between studies. Results: Twenty-two papers of full text of these articles were then obtained, and reviewed. Of these, 18 articles fulfilled the inclusion criteria and subsequently were qualitatively analyzed. Eleven articles were included for evaluating of PPD. The WMD was 0.86 mm, with a 95% CI= 0.44 mm to 1.29 mm. For BL, 2Show MoreRelatedEssay On Wound Regeneration1161 Words   |  5 PagesThe greatest challenge in clinical research trials is the development of bioactive surgical additives to reduce the post operative signs and symptoms by regulating inflammation and increase the speed of healing process. [1] An extensive intra cellular and extra cellular set of event are carried out in the healing of soft and hard tissue which are medicated by signalling proteins. [2]Yet complete self-regeneration in many tissues and organs after injury is limited. In endogenous regenerative medicineRead MoreThe Effect Of Platelet Rich Plasma On Recovery2033 Words   |  9 PagesThe Effect of Platelet Rich Pla sma hamstring Recovery Justin Turner Research and Design April 29, 2014 2PLATELET RICH PLASMA Turner Abstract Muscle injuries are one of the most common injures athletes experience. Most muscle injuries come from excessive strain and pull on the muscles, which come from different movements such as jumping and running. The normal healing time for a muscle strain is about 3-6 weeks. Research has found a new healing agent called Platelet Rich plasma, which is aRead MoreAssay Parameters Determine The Platelet Mediated Clumping Phenotype For It / C10 Parasite Line Essay1702 Words   |  7 Pagesdetermine the platelet-mediated clumping phenotype for IT/C10 parasite line Frank G. Onyambu1,2,4, Peter C. Bull3,4, David J. Roberts1,2 1. Nuffield Division of Clinical Laboratory Sciences, University of Oxford, John Radcliffe Hospital, OX3 9DU, Oxford, UK 2. NHS Blood and Transplant, Blood Research Lab, John Radcliffe Hospital, OX3 9DU, Oxford, UK 3. Nuffield Department of Clinical Medicine, University of Oxford, John Radcliffe Hospital, OX3 9DU, Oxford, UK 4. KEMRI-Wellcome Trust Research ProgrammeRead MorePp For Knee Oa 2013719 Words   |  3 Pagesphysician, an orthopedic surgeon who discussed current research in regenerative medicine and osteoarthritis. Drew Marcos, Physical therapist, who discussed a practical way to analyze the pitching mechanics and the key moments in the movement of this overhead motion. In Cardone presentation, His main focus was on Platelet-rich plasma (PRP), (plasmas that come from the patient’s body, and is centrifuged to increase the concentration of platelets combined with remaining blood). He also discussed theRead MoreThe Field Of Cosmetics And The Treatment Of Injuries, Skin, And Hair1891 Words   |  8 Pagesorthopedics. Platelets are one of the essential components found in blood, known best for their importance in coagulation. They contain proteins known as growth factors that play an essential role in healing damaged tissue (Lubkowska et al., 2012). The normal range of platelets in healthy human blood ranges from 150,000 to 450,000 platelets per microliter of blood (Daly, 2011). Advancements in the methods and techniques for the isolation of particular cells have made it possible to purify platelets fromRead MoreStem Cancer Case Studies1698 Words   |  7 PagesAnother trial involved a 60-year-old man, who lived an active lifestyle. He had a de generative joint disease, a 60% meniscus tear. They injected his knee twice over one year with stem cells and Platelet Rich Plasma (PRP). To obtain platelet rich plasma, blood is spun to isolate platelets. These platelets contain growth factors, that when injected into damaged tissue or organ can help promote a person feeling back to their normal self. This therapy has given him long periods of relief and he was ableRead MoreSupply Chain of Blood and Products in a Blood Bank2515 Words   |  10 PagesThe objective of this case study is 1. To study the existing supply chain of blood and blood products in a regional blood bank 2. To identify cost and risk related problems in the supply chain of blood and blood products and to develop a solution for cost and risk minimization. BACKGROUND Human blood is not an ordinary commodity because it cannot be substituted and its need will always exist. Blood and blood products are also perishable, which complicates things even further. Shortages lead to highRead MoreRemoval Of The Lower Impacted Third Molars Case Study1359 Words   |  6 Pagesto the oral environment is more susceptible to periodontal infection and thus to greater periodontal attachment loss.(2–5) Similarly, deeply impacted L3Ms often leads to periodontal defects after its surgical removal.(6,7) In this sense, several studies have shown that periodontal healing of the 2Ms after 3M removal is accompanied by intraosseous defects and deep periodontal pockets, especially in patients older than 26 years with a mesioangular or horizontal impaction and pre-existing periodontalRead MoreBiological Therapy Case Study830 Words   |  4 Pageselimination of pain 68. From the current results of animal experiments, biological methods are expected to be able to resto re the structure of degenerative disc, but whether it can eliminate the pain is still not clear. Recent results from animal studies have shown that injection of growth factors can reduce the expression of inflammatory cytokines in degenerative intervertebral discs. Biologically active substance injection: for early intervention of intervertebral disc, can promote cell proliferationRead MoreA Research Study On Stem Cell Therapy1450 Words   |  6 Pagescell research actually started in the mid 1800’s. Scientists first discovered that certain cells within the body could develop into other cells. Stem cell research has since developed stem cell therapy treatments like bone marrow transplant , stem cell therapy for Parkinson’s, and stem cell therapy for Alzheimer’s disease. This is a very promising treatment for all kinds of degenerative diseases because of the stem cells’ regenerative abilities. From what we know about stem cell research so far